Increasingly, researchers in a wide range of fields at UC Berkeley are applying novel data science approaches to very large sensitive and restricted data sets. Working closely with Berkeley Research Computing (BRC), the Research Data Management (RDM) Program has been helping dozens of faculty, students, and postdocs working with sensitive data by providing consulting expertise in a number of disciplines, including the biological sciences, public health, social welfare, demography, computer science, and more. The combined approach of providing data management and computation support helps researchers integrate data management and curation best practices into their larger research workflows while protecting their data.